Publications
PARP1 suppression drives ROS resistance in aneuploid cancer cells
Pan Cheng, Angela Mermerian-Baghdassarian, Yufeng Wang, Ze Chen, Helberth M Quysbertf, Pradeep Singh Cheema, Joseph C Mays, Xin Zhao, Lizabeth Katsnelson, Sally Mei, Rohini Shrivastava, Mirna Bulatovic, Jiehui Deng, Markus Schober, Kwok-Kin Wong, Teresa Davoli#
(#corresponding)
2026 - Molecular Cell DOI: 10.1016/j.molcel.2026.04.006
Specific Aneuploidies Predict Immune Evasion and Poor Immunotherapy Response in Melanoma
Lizabeth Katsnelson, Shini Chen, Ze Chen, Dania Annuar, Jesus Mario Rangel Valenzuela, Andy Zhao, Joanne Xiu, David Fenyö, Joy Bianchi, Teresa Davoli#
(#corresponding)
2026 - preprint in bioRxiv. : https://www.biorxiv.org/content/10.64898/2026.04.12.718039v1
The role of retrotransposons at the interface of DNA damage and the innate immune response
Pooja Vikraman, Teresa Davoli, Paolo Mita#
(#corresponding)
Pan-cancer analysis reveals context-dependent roles of LINE-1 ORF1p in immune regulation and copy number alterations
Efiyenia Ismini Kaparos, Wenjing Zhang, Ryusei Miyanaga, Wilson McKerrow, Jef Boeke, Teresa Davoli, Paolo Mita, Kelly V. Ruggles, David Fenyö#
(#corresponding)
2025 - preprint in bioRxiv. : https://www.biorxiv.org/content/10.1101/2025.10.03.680361v2
KaryoTap Enables Cost-Effective High-Throughput Single-Cell Aneuploidy Profiling and Reveals How Positive and Negative Selection Shapes Cancer Genomes
Joseph C Mays*, Fabio Alfieri*, Maria Trifas, Manjunatha Kogenaru, Helberth M. Quysbertf, Sally Mei, Nazario Bosco, Xin Zhao, Joy Bianchi, Aleah Goldberg, Gururaj Rao Kidiyoor, Liam J. Holt, David Fenyö, Teresa Davoli#
(#corresponding)
2025 - preprint in bioRxiv.: https://doi.org/10.1101/2023.09.08.555746
Modeling and targeting general and chromosome-specific aneuploidy in cancer
Aleah Goldberg, Maria Trifas, Teresa Davoli#
(#corresponding)
2025 - Genes and Development. DOI: 10.1101/gad.352766.125
The Hallmarks of Aneuploidy in Cancer and Congenital Syndromes
Pan Cheng, Karan Singh, Roger H Reeves, Teresa Davoli#
(#corresponding)
2025 - Annual Review of Genomics and Human Genetics. https://doi.org/10.1146/annurev-genom-111723-103557
KaryoCreate: A CRISPR-based technology to study chromosome-specific aneuploidy by targeting human centromeres
Nazario Bosco*, Aleah Goldberg*, Xin Zhao*, Joseph C Mays*, Pan Cheng*, Adam F Johnson*, Joy J Bianchi, Cecilia Toscani, Elena Di Tommaso, Lizabeth Katsnelson, Dania Annuar, Sally Mei, Roni E Faitelson, Ilan Y Pesselev, Kareem S Mohamed, Angela Mermerian, Elaine M Camacho-Hernandez, Courtney A Gionco, Julie Manikas, Yi-Shuan Tseng, Zhengxi Sun, Somayeh Fani, Sarah Keegan, Scott M Lippman, David Fenyö, Simona Giunta, Stefano Santaguida, Teresa Davoli#
(*equal contribution, #corresponding)
2023 - Cell. https://doi.org/10.1016/j.cell.2023.03.029
Xin Zhao, Ezra E. W. Cohen, William N. William Jr, Joy J. Bianchi, Jim P. Abraham, Daniel Magee, David B. Spetzler, J. Silvio Gutkind, Ludmil B. Alexandrov, Webster K. Cavenee#, Scott M. Lippman#, Teresa Davoli#
(#corresponding)
2022 - Proceedings of the National Academy of Sciences 119 (47) e2213835119. https://doi.org/10.1073/pnas.221383511
NYU Langone NewsHub: Newfound Cancer Cell Biology Suggests Which Patients Will Respond to Immunotherapy
Proteogenomic analysis of aneuploidy reveals divergent types of gene expression regulation across cellular pathways
Pan Cheng*, Xin Zhao*, Lizabeth Katsnelson, Elaine M Camacho-Hernandez, Angela Mermerian, Joseph C Mays,
Reyna Edith Rosales-Alvarez, Raquel Moya, Jasmine Shwetar, Dominic Grun, David Fenyö, Teresa Davoli#
(*equal contribution, #corresponding)
2022 - Elife 11:e75227. https://doi.org/10.7554/eLife.75227
Immune evasion in HPV− head and neck precancer–cancer transition is driven by an aneuploid switch involving chromosome 9p loss
William N. William Jr#*, Xin Zhao*, Joy J. Bianchi*, Heather Y. Lin, Pan Cheng, J. Jack Lee, Hannah Carter, Ludmil B. Alexandrov, Jim P. Abraham, David B. Spetzler, Steven M. Dubinett, Don W. Cleveland, Webster Cavenee, Teresa Davoli#, Scott M. Lippman#
(*equal contribution, #corresponding)
2021 - Proceedings of the National Academy of Sciences 118 (19) e2022655118. https://doi.org/10.1073/pnas.2022655118
Not all cancers are created equal: tissue-specificity in cancer driver genes and pathways
Joy J.Bianchi*, Xin Zhao*, Joseph C.Mays, Teresa Davoli#
(*equal contribution, #corresponding)
2020 - Current Opinion in Cell Biology (63): 135-143. https://doi.org/10.1016/j.ceb.2020.01.005
Sack LM, Davoli T, Li MZ, Li Y, Xu Q, Naxerova K, Wooten EC, Bernardi RJ, Martin TD, Chen T, Leng Y, Liang AC, Scorsone KA, Westbrook TF, Wong KK, Elledge SJ
2018 -Â Â Cell 173 (2): 499-514.
Liao S, Davoli T, Leng Y, Li MZ, Xu Q, Elledge SJ
2017 - Genes Dev 31 (2): 184-196.
Davoli T, Uno H, Wooten EC, Elledge SJ
2017 - Science, 355 (6322).
Davoli T, Mengwasser KE, Duan J, Chen T, Christensen C, Wooten EC, Anselmo AN, Li MZ, Wong KK, Kahle KT, Elledge SJ
2016 - Genes Dev 30 (24): 2684-2695.
Sack LM, Davoli T, Xu Q, Li MZ, Elledge SJ
2016 - G3 (Bethesda) 6 (9): 2781-90.
Hosler GA, Davoli T, Mender I, Litzner B, Choi J, Kapur P, Shay JW, Wang RC
2015 - J Cutan Pathol 42 (2): 108-17.
Zhu J, Davoli T, Perriera JM, Chin CR, Gaiha GD, John SP, Sigiollot FD, Gao G, Xu Q, Qu H, Pertel T, Sims JS, Smith JA, Baker RE, Maranda L, Ng A, Elledge SJ, Brass AL
2014 - Cell Rep 9 (2): 752-66.
Davoli T, Xu AW, Mengwasser KE, Sack LM, Yoon JC, Park PJ, Elledge SJ
2013 - Cell. 155 (4): 948-62.
Solimini NL, Liang AC, Xu C, Pavlova NN, Xu Q, Davoli T, Li MZ, Wong KK, Elledge SJ
2013 - PNAS 110 (5): E407-14.
Davoli T, de Lange T
2012 - Cancer Cell 21(6): 765-76.
Davoli T, de Lange T.
2011 - Annu Rev Cell Dev Biol 27: 585-610. Review.
Davoli T, Denchi EL, de Lange T
2010 - Cell 141(1): 81-93.
Bonetti P, Davoli T, Sironi C, Amati B, Pelicci PG, Colombo E
2008 - J Cell Biol 182(1): 19-26.