Published Work

The Fruits of Our Labor

Immune evasion in HPV− head and neck precancer–cancer transition is driven by an aneuploid switch involving chromosome 9p loss

William WN*, Zhao X*, Bianchi JJ*, Lin HY, Cheng P, ... Davoli T, Lippman SM

*equal contribution

2021 - Proceedings of the National Academy of Sciences 118 (19) e2022655118. https://doi.org/10.1073/pnas.2022655118

Not all cancers are created equal: tissue-specificity in cancer driver genes and pathways

Bianchi JJ*, Zhao X*, Mays JC, Davoli T

*equal contribution

2020 - Current Opinion in Cell Biology (63): 135-143. https://doi.org/10.1016/j.ceb.2020.01.005

Profound Tissue Specificity in Proliferation Control Underlies Cancer Drivers and Aneuploidy Patterns

Sack LM, Davoli T, Li MZ, Li Y, Xu Q, Naxerova K, Wooten EC, Bernardi RJ, Martin TD, Chen T, Leng Y, Liang AC, Scorsone KA, Westbrook TF, Wong KK, Elledge SJ

2018 - Cell 173 (2): 499-514.

A genetic interaction analysis identifies cancer drivers that modify EGFR dependency

Liao S, Davoli T, Leng Y, Li MZ, Xu Q, Elledge SJ

2017 - Genes Dev 31 (2): 184-196.

Tumor aneuploidy correlates with markers of immune evasion and with reduced response to immunotherapy

Davoli T, Uno H, Wooten EC, Elledge SJ

2017 - Science, 355 (6322).

Functional genomics reveals that tumors with activating phosphoinositide 3-kinase mutations are dependent on accelerated protein turnover

Davoli T, Mengwasser KE, Duan J, Chen T, Christensen C, Wooten EC, Anselmo AN, Li MZ, Wong KK, Kahle KT, Elledge SJ

2016 - Genes Dev 30 (24): 2684-2695.

Sources of Error in Mammalian Genetic Screens

Sack LM, Davoli T, Xu Q, Li MZ, Elledge SJ

2016 - G3 (Bethesda) 6 (9): 2781-90.

A primary melanoma and its asynchronous metastasis highlight the role of BRAF, CDKN2A, and TERT

Hosler GA, Davoli T, Mender I, Litzner B, Choi J, Kapur P, Shay JW, Wang RC

2015 - J Cutan Pathol 42 (2): 108-17.

Comprehensive identification of host modulators of HIV-1 replication using multiple orthologous RNAi reagents.

Zhu J, Davoli T, Perriera JM, Chin CR, Gaiha GD, John SP, Sigiollot FD, Gao G, Xu Q, Qu H, Pertel T, Sims JS, Smith JA, Baker RE, Maranda L, Ng A, Elledge SJ, Brass AL

2014 - Cell Rep 9 (2): 752-66.